European journal of clinical investigation
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Eur. J. Clin. Invest. · Sep 2019
Meta AnalysisUric acid level, gout and bone mineral density: A Mendelian randomization study.
This study aimed to examine whether the uric acid level or gout is causally associated with bone mineral density (BMD). ⋯ Mendelian randomization analysis did not support a causal association between uric acid level, gout and lumbar spine or FN BMD.
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Eur. J. Clin. Invest. · Sep 2019
Impact of platelet turnover on long-term adverse cardiovascular outcomes in patients undergoing percutaneous coronary intervention.
Increased platelet turnover and high platelet reactivity are associated with short-term major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) or stable coronary artery disease (SCAD). We investigated the impact of platelet turnover on long-term MACE. ⋯ Increased platelet turnover is associated with long-term adverse outcome in patients with coronary artery disease undergoing PCI. Platelet turnover represents a new marker of atherothrombotic risk and might help to guide composition or duration of antiplatelet therapy.