Lancet
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In 33 patients studied with endocrine neoplasms of the pancreas more than half the tumours contained pancreatic polypeptide (P. P.) producing cells, and a high radioimmunoassayable concentration of P. P. was found in the tumour extracts. ⋯ P. cells. Measurements of plasma P. P. levels should be a new aid to diagnosis of pancreatic tumours.
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Clinical Trial Controlled Clinical Trial
Treatment of attacks in hyperkalaemic familial periodic paralysis by inhalation of salbutamol.
In fifteen patients with hyperkalaemic familial periodic paralysis, inhalation of salbutamol alleviated hyperkaleamia and paralysis precipitated by exercise or oral administration of potassium chloride. In-vitro studies with rat soleus muscles indicated that the hypokalaemic effect of salbutamol is related to stimulation of the active coupled transport of sodium and potassium in muscle cells. Follow-up studies proved that the inhalation of salbutamol is a simple and adequate method for the treatment of the paralytic episodes in these patients.