Medicine
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Pompe disease or glycogen storage disease type II is a rare autosomal recessive disorder caused by a deficiency of the lysosomal enzyme a-glucosidase. Although enzyme replacement therapy (ERT) with 2 weekly intervals following was considered an effective treatment for Pompe disease in 2006, few patients can afford to receive treatment in China because of the high cost. This study aimed to examine the standard management of enzyme replacement therapy for late-onset Pompe disease among patients over the age of 14 years from a nursing perspective in order to assess operating procedures. ⋯ The time of dispensing and infusing the injection fluids using the cooperative method was 15.97 minutes shorter than that using the conventional method (95% CI: 4.51-27.43, P = .012); the time using the modified method was 20.93 minutes shorter than that using the conventional method (95% CI: 9.47-32.39, P = .012); and there was no significant difference between the cooperative and modified methods (P = .431). Enzyme replacement therapy entails frequent treatment and strict nursing requirements related to the intravenous infusion process. In this context, a standard operating procedure can be used to control nursing times and labor costs effectively while ensuring a safe and effective infusion process.
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Although many publications in diabetic retinopathy (DR) have been reported, there is no bibliometric analysis. ⋯ Based on data extracted from the WoSCC, this study provides a broad view of the current status and trends in DR research and may provide clinicians and researchers with insight into DR research and valuable information to identify potential collaborators and partner institutions and better predict their dynamic directions.
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Mycoplasma pneumoniae infection may induce a systemic hypercoagulable abnormality, like organ embolism and infarction. Indexes of blood coagulation and C-reactive protein (CRP) have been reported different between healthy people and mycoplasma pneumoniae pneumonia (MPP) patients, but this difference in MPP patients with different chest imaging findings has rarely been reported. We performed a retrospective study of 101 children with MPP and 119 controls, combined with radiological examination and blood tests, to compare the blood coagulation and CRP level among MPP children with different chest imaging findings. ⋯ And the FIB and D-D values in group of lung consolidation were significantly higher than that in the other 3 groups (all P < .05). When compared with controls, the white blood cell, CRP, FIB, and D-D levels in MPP children were significantly higher, and the activated partial thromboplastin time and thrombin time levels were significantly lower (all P < .05). Our results showed that CRP level changed most significantly in group of interstitial pneumonia, whereas FIB, D-D levels changed most significantly in the lung consolidation group.
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Observational Study
The potential impact from glenohumeral internal rotation deficit to the knee kinematics in baseball pitchers: A case-control study.
A recent study suggested that baseball pitchers with glenohumeral internal rotation deficit (GIRD) may tend to use trunk rotation as compensation to adjust ball placement, which may lead to subsequent counter movement at the knee of the leading leg. This study aims to investigate the kinematic characteristics of the counter movements between the femur and the tibia (knee torsion), from the landing of the leading leg until the follow-through phase, during throwing between pitchers with and without GIRD at the dominant arm. This is a case-control study. ⋯ The maximal angular movement between the femur and the tibia (knee torsion) of the leading leg was measured, using The Zebris 3D (Zebris Medizintechnik GmbH, Isny, Germany) motion analysis system, in the interval from the landing until the follow-through phase during pitching a fastball to the bottom-outside corner with their dominant arm. The results showed that the maximal knee torsion of the leading leg in the experimental group (13.67 ± 0.9 degrees) was significantly greater than the control group (4.25 ± 1.369 degrees) (P < .05). Pitchers with GIRD had greater counter movement in the knee joint than pitchers without GIRD.
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This study aimed to investigate the perception about hand washing and health status among Koreans using the data from the Community Health Survey. We examined the differences in the perceptions about hand washing and health statuses of 220,440 participants of the 2017 community health survey. The sample was divided into groups based on demographic variables, perceptions about hand washing, and prevalence of metabolic diseases. ⋯ This study showed that positive hand washing perception is associated with good health care practices. The perceptions of hand washing, which are formed during early childhood, were closely associated with health status. This finding could be useful evidence for developing programs focusing on major health behaviors and levels of health.