Medicine
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Case Reports
Contrast-enhanced computed tomography assisted diagnosis of bleeding caused by colonic angiodysplasia: A case report.
Angiodysplasia (AD) in the gastrointestinal tract is a degenerative vascular condition characterized by vascular dilation, tortuosity, and arteriovenous connections within the mucosal and submucosal layers. AD is a significant cause of lower gastrointestinal bleeding in the elderly, often presenting as chronic, intermittent hemorrhage. The research challenge lies in the potential for multiple and minute AD lesions to be missed during endoscopy, which may lead to post-hemostatic rebleeding. ⋯ We highlight that CECT for diagnosing AD-related bleeding offers higher safety and convenience, potentially superior to digital subtraction angiography, particularly in critically ill elderly patients.
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Case Reports
Diffuse large B-cell lymphoma with clear cell morphology - a close mimic of clear cell carcinoma: A case report.
In this case, the tumor cells were epithelioid, with translucent cytoplasm, well-defined cell borders, moderate size, rounded or ovoid nuclei, and small nucleoli visible. Based on this morphological feature, we first considered clear cell carcinoma, but the epithelial-related immunohistochemical results don't support the diagnosis. Ultimately, based on lymphoma-associated immunohistochemical results and gene rearrangement assays, the final diagnosis of a clear cell variant of DLBCL. Therefore, clinicians and pathologists are reminded that DLBCL with clear cell morphology is rare. ⋯ Diffuse large B-cell lymphoma with clear cell morphology is a rare tumor, and its diagnosis mainly relies on pathological findings, immunohistochemistry, gene rearrangement.
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To investigate the causal relationship between rheumatoid arthritis (RA) and interstitial lung disease (ILD) in the East Asian population, we utilized Mendelian randomization (MR). Publicly available summarized data from genome-wide association studies on RA (4199 cases and 208,254 controls), and the data on ILD (1046 cases and 176,974 controls) were obtained from BioBank Japan. Eligible single nucleotide polymorphisms from East Asian populations were obtained from genome-wide association studies as instrumental variables, and 11 RA-related single nucleotide polymorphisms (P < 5 × 10-8) were selected as instrumental variables. ⋯ The reliability evaluation could adopt the fixed-effect model, and the absolute value of the MR-Egger regression intercept was 0.021, P > 0.05, and P value of Global Test in MR-PRESSO was 0.573. The test results of the leave-one-out showed that the results are robust, and the funnel plot indicated that the instrumental variables were not affected by potential factors. In conclusion, this study demonstrates that RA is a risk factor for ILD in the East Asian population.
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The ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol, abbreviated as NHHR, represents a brand-new lipid biomarker for assessing cardiovascular disease risk. Research has suggested a link between lipid metabolism and obstructive sleep apnea (OSA). To delve deeper, this study was carried out using data derived from the NHANES to ascertain whether NHHR and OSA are associated. ⋯ Findings from this study uncovered a strong connection between NHHR and an increased possibility of developing OSA in American adults. Further exploration of NHHR could offer insights into OSA prevention and treatment. However, owing to the constraints inherent in cross-sectional studies, more studies are required to establish a concrete link between NHHR and OSA.
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Comparative Study
Enhancing English abstract quality for non-English speaking authors using ChatGPT: A comparative study of Taiwan, Japan, China, and South Korea with slope graphs.
A clear and proficient English abstract is crucial for disseminating research findings to a global audience, significantly impacting the accessibility and visibility of research from non-English speaking countries. Despite the adoption of ChatGPT since November 30, 2022, a comprehensive analysis of improvements in English abstracts in scholarly journals has not been conducted. This study aims to identify which authors from Taiwan, Japan, China, and South Korea (TJCS) have shown the most improvement in English abstracts. ⋯ The English abstracts in Medicine (Baltimore) have improved, reflecting the tool's positive impact on enhancing technical language. This study demonstrates that ChatGPT can enhance the quality of English abstracts for authors from non-English speaking regions, although the assumption that all authors use ChatGPT is invalid and impractical. The findings underscore the value of artificial intelligence tools in academic writing and recommend further investigation into the long-term implications of artificial intelligence integration in scholarly communication.