Medicine
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A large number of studies have shown that high expression of vascular endothelial growth factor (VEGF) in cancer tissues is associated with poor prognosis of various cancers. However, this finding in endometrial cancer is controversial. Therefore, this meta-analysis aimed to explore the effects of VEGF on survival in patients with endometrial cancer. ⋯ High VEGF expression can predict poor prognosis and poor clinicopathological features in patients with endometrial cancer, and it may be a valuable new indicator to evaluate the prognosis of patients with endometrial cancer.
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In order to take full advantage of traditional Chinese medicine (TCM) and western medicine, combined with machine learning technology, to study the risk factors and better risk prediction model of diabetic retinopathy (DR), and provide basis for the screening and treatment of it. Through a retrospective study of DR cases in the real world, the electronic medical records of patients who met screening criteria were collected. Moreover, Recursive Feature Elimination with Cross-Validation (RFECV) was used for feature selection. ⋯ Through SHAP analysis, it was found that TCM syndrome types, albumin, low density lipoprotein, triglyceride, total protein, glycosylated hemoglobin were closely related to the increased risk of DR. It can be concluded that TCM syndrome type is the risk factor of DR. The GBM classifier based on grid search optimization, with relevant risk factors of TCM and western medicine as variables, can better predict the risk of DR.
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Cardiac arrest (CA) is an acute emergency with high mortality and is closely associated with the risk of brain damage or systemic ischemia-reperfusion injury, post-traumatic stress symptoms. ⋯ Individualized targeted temperature management under the guidance of multimodal brain monitoring plays an important role in brain protection of patients with CA.
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The objective of this study is to examine the impact of intellectual capital (IC) and its elements on private hospital performance. In addition, this study explores the moderating role of digital transformation in the relationship between IC and its elements and private hospital performance. This study selects 13 private listed hospitals from 2012 to 2022 as the sample. ⋯ The results show that IC and only one element (structural capital) have a positive impact on private hospital performance, while human and relational capitals have no significant impact. Surprisingly, digital transformation negatively moderates the relationship between IC and private hospital performance. This study underscores the pivotal role of IC in enhancing the performance of private hospitals, and hospital managers should accelerate hospital digital transformation in the digital era.
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Chronic kidney disease (CKD) and hypothyroidism are prevalent chronic conditions with a generally believed correlation between them. However, large-scale population studies and investigations into causation are lacking. This study analyzed CKD and thyroid function data from the National Health and Nutrition Examination Survey database spanning 2007 to 2012 using multiple regression analyses to examine the correlation between CKD and hypothyroidism. ⋯ Chronic kidney disease (CKD) and hypothyroidism are prevalent chronic conditions with a generally believed correlation between them. There is no large-scale population studies and the causation relationship between CKD and hypothyroidism are lacking. The finding of the causal relationship between CKD and hypothyroidism may be beneficial to the prevention of the disease and the prognosis of the patients.