Medicine
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Case Reports
Catastrophic antiphospholipid syndrome of pregnancy with acute massive cerebral infarction: A case report.
Catastrophic antiphospholipid syndrome (CAPS) is the most serious type of antiphospholipid antibody syndrome (APS) and can be easily confused with other disorders, such as hemolytic uremic syndrome, disseminated intravascular coagulation and thrombocytopenia syndromes. Timely diagnosis of CAPS poses considerable challenges due to its rarity and the fact that clinicians often lack knowledge of the disease. ⋯ The rarity of CAPS is such that misdiagnosis often occurs, culminating in serious complications and even death, emphasizing the need for early recognition, timely diagnosis and immediate treatment. In CAPS that improves with treatment, monitoring and prevention of recurrence is also essential.
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Observational studies indicate that the risk of prostatitis in sleep apnea patients is higher than those without sleep apnea. However, the causal relationships remain to be determined. This study aims to investigate the causal relationships of sleep apnea on prostatitis using Mendelian randomization (MR). ⋯ The inverse variance weighted (IVW) analysis was employed as the primary statistical method. In 2-sample MR analyses, we found that IVW estimates revealed that sleep apnea inferred an effect on risk of prostatitis at statistical significance (odds ratio [OR] = 1.370, 95% confidence interval [CI] = 0.094-0.535, P = .005). This MR study strengthens the evidence of a causal relationship between sleep apnea and prostatitis in Europeans.
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Atopic dermatitis (AD) is a prevalent inflammatory skin condition that commonly occurs in children. More and more scientific evidence suggests that gut microbiota plays an important role in the pathogenesis of AD, whereas there is no article providing a comprehensive summary and analysis. We aimed to analyze documents on AD and gut microbiota and identify hotspots and development trends in this field. ⋯ We highlighted that gut microbiota may exacerbate symptoms of AD through various aspects, including immunity, metabolites, and neuroendocrine pathways. More efforts are required to investigate the safety and efficacy of gut microbial management methods for the prevention and treatment of AD.
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At present, the association of smoking, alcohol intake, and coffee intake with the risk of bacterial pneumonia (BP) remains controversial. In this study, we used a 2-sample Mendelian randomization (MR) analysis to estimate the association of smoking, alcohol intake, and coffee intake with the risk of BP. ⋯ Our findings provide relevant evidence for a favorable causal association of genetically predicted smoking initiation and cigarettes per day with BP risk. However, there may not be a causal association between past tobacco smoking, alcohol intake, and coffee intake with increased BP incidence rates.
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Coach autonomy-supportive behaviors are a crucial factor in the communication effectiveness with athletes experiencing depressive moods. Therefore, clarifying the relationship between coach autonomy-supportive behaviors and the communication effectiveness with athletes experiencing depressive moods is of significant importance for promoting effective communication between coaches and athletes. This study employs in-depth interviews, questionnaires, and stepwise regression analysis, using purposive sampling to investigate coaches and athletes experiencing depressive moods from various regions, levels, genders, and sports in China. The study examines the impact of coach autonomy-supportive behaviors on their communication effectiveness, as well as the mediating role of intrinsic motivation variables, measuring and testing these variables. ⋯ (1) Coach autonomy-supportive behaviors can positively predict the communication effectiveness between coaches and athletes experiencing depressive moods; (2) Intrinsic motivation partially mediates the relationship between coach autonomy-supportive behaviors and communication effectiveness between coaches and athletes experiencing depressive moods. The study concludes that coaches can promote athletes' intrinsic motivation by supporting and encouraging them to make their own choices and affirming the outcomes of those choices. This approach can alleviate athletes' depressive moods and foster their willingness to actively communicate and share their feelings with coaches, thereby enhancing communication effectiveness.