Medicine
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Inflammation plays a critical role in vertebral fractures. However, there is a lack of sufficient evidence regarding the prognostic significance of the systemic immuno-inflammatory index (SII), a novel marker of systemic inflammation, in patients with vertebral fractures. In this study, we aimed to assess the predictive value of SII in critically ill patients with vertebral fractures. ⋯ Besides, the Pearson correlation test confirmed a significant correlation between SII and vertebral T-values measured by bone mineral density and pain indicator. The study findings revealed that SII is an independent predictor of mortality in patients with vertebral fractures. This indicates that SII can serve as a reliable and easily accessible prognostic indicator for newly diagnosed critically ill patients with vertebral fractures.
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Diffuse multivessel coronary artery spasm (DMV-CAS) was defined as a severe and reversible diffuse spasm occurring in more than 2 major coronary arteries, which is rare in clinical practice. Due to a wide lesion scope, DMV-CAS often occurs in the form of complications. It is not easy to be clinically diagnosed because it is too brief to be caught. Here, we report a rare case of spontaneous subtotal occlusion of 3 major coronary arteries induced by Vasalva action, which was confirmed in real-time by CAG. ⋯ This case highlights the identification of multivessel diffuse coronary spasm and acute myocardial infarction, and the prevention of CAS triggers, which requires the attention of clinicians.
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Human bladder cancer (BC) is the most common urogenital system malignancy. E2F transcription factors (E2Fs) have been reported to be involved in the growth of various cancers. However, the expression patterns, prognostic value and immune infiltration in the tumor microenvironment of the 8 E2Fs in BC have yet fully to be explored. ⋯ E2F3/5/8 might serve as promising prognostic biomarkers and new therapeutic direction for BC patients.
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To explore the application effect of "quality control circle" activity in postoperative nursing of elderly dental implants. ⋯ Quality control circle activities can effectively improve the success rate of dental implants, reduce the occurrence of postoperative complications, improve patient satisfaction, and help medical staff in providing better treatment for patients.
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Stone quarry activities in Nigeria are mostly unregulated such that the workers in these quarries are continuously exposed to the inhalation of silica dust. It has been observed that silica dust particles negatively impact the health of stone quarry workers which usually manifest as respiratory difficulties, asthma-like illnesses and other adventitious events of the lungs. The study was designed to evaluate the probable immunological impact of silica dust inhalation from stone crushing by workers. ⋯ The results indicated that neutrophils and eosinophils numbers increased significantly (P < .05) and CD4 counts declined significantly (P < .001). Alteration in these proportions is a pointer to the injurious impact of silica dust on the immune system of these workers. The findings in this study should spur actions in the education of these workers on the need for the use of proper personal protection equipment and the establishment of a scheme to periodically carry out a health assessment check to identity those at most risk of developing chronic illnesses.