JAMA : the journal of the American Medical Association
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To assess associations between current weight, weight at age 18 years, and weight change from age 18 years to ages 30 to 55 years with current levels of plasma cholesterol (C), high- and low-density lipoprotein C (HDLC and LDLC), triglycerides (TG), and systolic and diastolic BP (SBP and DBP), we calculated weight change from self-reported weight at age 18 years and measured weight at ages 30 to 55 years in 308 white and 69 black subjects in a random recall group and 244 whites and 66 blacks in a hyperlipidemic recall group in the Princeton School Study. In random-recall-group whites, mean weight gain over time was greater in men than in women; black women had greater weight gain than black men, and nearly twice the weight gain of white women. ⋯ Although weight at age 18 years had no consistent independent explanatory relationship to C, TG, HDLC, and LDLC values, random-recall-group white men who were in the lowest quartile for weight at age 18 years had current levels of C, TG, SBP, and DBP that were all lower than those observed in white men who had been in the upper quartile of weight at age 18 years. Atherogenic increments in TG levels, SBP, and DBP from age 18 years to ages 30 to 55 years are a function, in part, of weight gain during these years.
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Comparative Study
Inadequate oxygenation and ventilation using the esophageal gastric tube airway in the prehospital setting.
In a prospective study to evaluate the respiratory effectiveness of the esophageal gastric tube airway (EGTA) in the prehospital setting, we analyzed arterial blood samples from 43 victims of out-of-hospital cardiopulmonary arrest managed with the EGTA. Five minutes after emergency department endotracheal intubation, arterial blood gas analysis was repeated for comparison. ⋯ During EGTA ventilation, the mean arterial PCO2 measured 77.1 +/- 34 mm Hg; endotracheal intubation decreased the mean PCO2 to 57.8 +/- 34.4 mm Hg. We conclude that endotracheal intubation remains the procedure of choice for airway management in the victim of cardiopulmonary arrest.