JAMA : the journal of the American Medical Association
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Review Meta Analysis
Health care-associated infection after red blood cell transfusion: a systematic review and meta-analysis.
The association between red blood cell (RBC) transfusion strategies and health care-associated infection is not fully understood. ⋯ Among hospitalized patients, a restrictive RBC transfusion strategy was associated with a reduced risk of health care-associated infection compared with a liberal transfusion strategy. Implementing restrictive strategies may have the potential to lower the incidence of health care-associated infection.
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Randomized Controlled Trial Multicenter Study
Tadalafil for prevention of erectile dysfunction after radiotherapy for prostate cancer: the Radiation Therapy Oncology Group [0831] randomized clinical trial.
Tadalafil is used to treat erectile dysfunction after prostate cancer treatment, but its role as a preventive agent is undefined. ⋯ Among men undergoing radiotherapy for prostate cancer, daily use of tadalafil compared with placebo did not result in improved erectile function. These findings do not support daily use of tadalafil to prevent erectile dysfunction in these patients.