JAMA : the journal of the American Medical Association
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What medical therapies are associated with greatest efficacy and fewest adverse events for treating hirsutism? ⋯ Oral contraceptive pills (OCPs) have been associated with improvement for mild hirsutism, as has flutamide (250 mg) twice daily and spironolactone for more severe cases. Finasteride and gonadotropin-releasing analogues are associated with inconsistent results and metformin is not associated with benefit.