JAMA : the journal of the American Medical Association
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Meta Analysis Comparative Study
Pharmacotherapy for Alcohol Use Disorder: A Systematic Review and Meta-Analysis.
Alcohol use disorder affects more than 28.3 million people in the United States and is associated with increased rates of morbidity and mortality. ⋯ In conjunction with psychosocial interventions, these findings support the use of oral naltrexone at 50 mg/d and acamprosate as first-line pharmacotherapies for alcohol use disorder.