Clinical neurology and neurosurgery
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Clin Neurol Neurosurg · Nov 2015
Comparative StudyClinical and radiography results of mini-plate fixation compared to suture suspensory fixation in cervical laminoplasty: A five-year follow-up study.
Lamina closure is the most common reason for failure of unilateral open-door laminoplasty. Mini-plate fixation was designed to solve such problem. We assessed the clinical outcomes and radiography results of mini-plate fixation by comparing it with suture suspension fixation. ⋯ Laminoplasty by mini-plate fixation preserved more cervical ROM and better cervical alignment, maintained cervical spine canal expansive stability and effectively avoided lamina reclosure for a long-term follow-up.
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Clin Neurol Neurosurg · Nov 2015
Risk factors for reoperation after initial burr hole trephination in chronic subdural hematomas.
The optimal management of chronic subdural hematomas remains a challenge. Twist drill craniotomy or burr hole trephination are considered optimal initial treatments, but the reoperation rate for hematoma recurrence and other complications is still high. Therefore, evaluation of possible risk factors for initial treatment failure is crucial. In this context, we performed a study to define a possible subpopulation that may benefit from a more invasive initial treatment regime. ⋯ Burr hole trephination is the therapy of choice in most chronic subdural hematomas, but the rate of recurrent hematomas is high. Every hematoma should be treated individually especially in relation to midline-shift and pre-existing conditions. Further prospective studies evaluating types of treatment and hematoma density are needed.
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Clin Neurol Neurosurg · Nov 2015
Efficacy of percutaneous vertebroplasty in patients with painful vertebral metastases: A retrospective study in 47 cases.
This study was to evaluate the efficacy of percutaneous vertebroplasty (PVP) in treating vertebral metastases, focusing on the related intractable pain and operative complications including cement leakage, cardiopulmonary dysfunction, dysneuria, etc. ⋯ With some limitations in the study, PVP appeared to be an alternative method to treat painful spine metastases.
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Clin Neurol Neurosurg · Nov 2015
Hemodynamic stress distribution reflects ischemic clinical symptoms of patients with moyamoya disease.
Currently, the probability of diagnosing asymptomatic moyamoya disease is increasing. In this study, we consider a less invasive method for predicting future ischemic symptoms in patients with moyamoya disease. ⋯ The data showed that hdSD at rest and CBF-MCA after acetazolamide loading reflects ischemic symptoms of patients with moyamoya disease. Thus, these parameters could be used as ischemic symptom markers for following patients with moyamoya disease. hdSD at rest is important because it is less invasive and can be performed without acetazolamide loading.
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Clin Neurol Neurosurg · Nov 2015
Combined IDH1 mutation and MGMT methylation status on long-term survival of patients with cerebral low-grade glioma.
The management of low-grade glioma (LGG) still remains controversial because the effectiveness of early and extensive resection is unclear, and the use of radiation therapy or chemotherapy is not well-defined. In particular, the importance of prognostic factors for survival remains a matter of discussion. The purpose of this study was to validate prognostic factors for survival in patients with LGG. ⋯ Tumor histology, size and IDH-mutation status are important predictors for prolonged overall survival in patients with LGG and may provide a reliable tool for standardizing future treatment strategies.