Clinical neurology and neurosurgery
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Clin Neurol Neurosurg · Jan 2010
Primary hydatidosis of the central nervous system: a retrospective study of 39 Tunisian cases.
To analyze epidemiological characteristics, clinical symptoms, radiological aspects, treatment and outcome of central nervous system hydatidosis and compare our results with those reported in literature. ⋯ Despite all the advances in imaging techniques and therapeutic methods, central nervous system hydatidosis remains difficult to cure and patient outcomes are not satisfactory especially in case of spinal involvement due to the high incidence of recurrence.
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Clin Neurol Neurosurg · Dec 2009
Case ReportsIntraoperative indocyanine green angiography in intracranial aneurysm surgery: Microsurgical clipping and revascularization.
The goal of this report is to illustrate the use of intraoperative indocyanine green (ICG) angiography in the surgical management of intracranial aneurysms, including microsurgical clipping and revascularization. ⋯ ICG angiography can provide real-time information and guide revision in the same surgical procedure for the management of intracranial aneurysms.
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Clin Neurol Neurosurg · Dec 2009
Ultrastructure and immunohistochemistry of the trigeminal peripheral myelinated axons in patients with neuralgia.
Detailed ultrastructural and immunohistochemical examination of the trigeminal axons surrounded by the peripheral type of the myelin could add new information about the extent of the trigeminal nerve lesion in neuralgia. ⋯ The pathological changes affect not only the central nerve fibers of the TNR, but also some of the peripheral axons, their myelin sheath and Schwann cells. These are signs of the retrograde ultrastructural and biochemical alterations, which could participate in the pathophysiological mechanism underlying the trigeminal neuralgia.
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Clin Neurol Neurosurg · Dec 2009
Frontal lobe atrophy is associated with small vessel disease in ischemic stroke patients.
The pathogenesis of frontal lobe atrophy (FLA) in stroke patients is unclear. We aimed to ascertain whether subcortical ischemic changes were more associated with FLA than with parietal lobe atrophy (PLA) and temporal lobe atrophy (TLA). ⋯ Frontal lobe atrophy in ischemic stroke patients may be associated with small vessel disease. The association between WMLs and FLA was predominant over atrophy of the parietal and temporal lobes, which suggests that the frontal lobe may be vulnerable to subcortical ischemic changes.
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Clin Neurol Neurosurg · Nov 2009
Randomized Controlled Trial Multicenter StudyDo women benefit more from systemic thrombolysis in acute ischemic stroke? A Serbian experience with thrombolysis in ischemic stroke (SETIS) study.
The female sex is associated with increased stroke severity and relatively poor functional recovery. Several studies have demonstrated that women with stroke benefit more from intravenous thrombolysis compared with men, while others found the nullification of gender effect among women treated with recombinant tissue plasminogen activator (rtPA). The purpose of our study was to determine any gender differences in the efficacy and safety of systemic thrombolysis among patients with acute ischemic stroke in Serbia. ⋯ There were no sex differences in functional outcome at 90 days after the stroke among patients treated with IV rtPA. This finding might confirm that thrombolytic therapy nullifies usual sex differences in stroke outcome and suggests that women with stroke may benefit more from rtPA treatment.