Clinical neurology and neurosurgery
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Clin Neurol Neurosurg · Nov 2015
Comparative Study Clinical TrialComparison of posterior lumbar interbody fusion (PLIF) with autogenous bone chips and PLIF with cage for treatment of double-level isthmic spondylolisthesis.
Spondylolytic defects involving multiple vertebral levels are rare. It is reported that only 1.48% of patients with back pain were diagnosed with multi-level spondylolysis. The incidence of multiple-level spondylolisthesis is even rarer, so far there have been few reports of multi-level isthmic spondylolisthesis in the literature. The aim of this study is to evaluate clinical and radiological outcomes of two different fusion techniques for treatment of double-level isthmic spondylolisthesis. ⋯ Clinical and functional outcomes demonstrate no significant differences between groups in treating back and leg pain of adult patients with double-level isthmic spondylolisthesis.
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Clin Neurol Neurosurg · Nov 2015
Association of early inflammatory parameters after subarachnoid hemorrhage with functional outcome: A prospective cohort study.
Early brain injury after aneurysmal subarachnoid hemorrhage (aSAH) comprises a pronounced neuroinflammatory reaction. Nevertheless, its relevance for functional outcome and its role as outcome predictor remains uncertain. We evaluated the relationship of various early inflammatory parameters regarding functional outcome according to the modified Rankin Scale score (mRS) at discharge (primary objective) and six months after aSAH. ⋯ Higher early IL-6 serum levels after aSAH are associated with poor outcome at discharge. In addition, involvement of LIF in the early inflammatory reaction after aSAH has been demonstrated.
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Clin Neurol Neurosurg · Nov 2015
Comparative StudyClinical and radiography results of mini-plate fixation compared to suture suspensory fixation in cervical laminoplasty: A five-year follow-up study.
Lamina closure is the most common reason for failure of unilateral open-door laminoplasty. Mini-plate fixation was designed to solve such problem. We assessed the clinical outcomes and radiography results of mini-plate fixation by comparing it with suture suspension fixation. ⋯ Laminoplasty by mini-plate fixation preserved more cervical ROM and better cervical alignment, maintained cervical spine canal expansive stability and effectively avoided lamina reclosure for a long-term follow-up.
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Clin Neurol Neurosurg · Nov 2015
Risk factors for reoperation after initial burr hole trephination in chronic subdural hematomas.
The optimal management of chronic subdural hematomas remains a challenge. Twist drill craniotomy or burr hole trephination are considered optimal initial treatments, but the reoperation rate for hematoma recurrence and other complications is still high. Therefore, evaluation of possible risk factors for initial treatment failure is crucial. In this context, we performed a study to define a possible subpopulation that may benefit from a more invasive initial treatment regime. ⋯ Burr hole trephination is the therapy of choice in most chronic subdural hematomas, but the rate of recurrent hematomas is high. Every hematoma should be treated individually especially in relation to midline-shift and pre-existing conditions. Further prospective studies evaluating types of treatment and hematoma density are needed.
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Clin Neurol Neurosurg · Nov 2015
Efficacy of percutaneous vertebroplasty in patients with painful vertebral metastases: A retrospective study in 47 cases.
This study was to evaluate the efficacy of percutaneous vertebroplasty (PVP) in treating vertebral metastases, focusing on the related intractable pain and operative complications including cement leakage, cardiopulmonary dysfunction, dysneuria, etc. ⋯ With some limitations in the study, PVP appeared to be an alternative method to treat painful spine metastases.