Clinical neurology and neurosurgery
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Clin Neurol Neurosurg · Nov 2014
Endoscopic third ventriculostomy in the management of hydrocephalus: Outcome analysis of 168 consecutive procedures.
Endoscopic third ventriculostomy (ETV) is the treatment of choice for obstructive hydrocephalus, but the outcome is still controversial in terms of age and aetiology. ⋯ ETV is a safe procedure and an effective treatment for obstructive hydrocephalus even following the dysfunction of previous VPSs and in children younger than two years.
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Clin Neurol Neurosurg · Nov 2014
Case ReportsTrue aneurysms of the superficial temporal artery: Diagnosis and treatment.
True aneurysms arising from the superficial temporal artery (STA) are quite uncommon. The present study reviews the surgical experience with true STA aneurysms to describe the clinical features and treatment options. ⋯ True STA aneurysms are usually discovered as a pulsating mass over the temple and their diagnosis could be done with ultrasonography, and computed tomography and magnetic resonance angiography. Simple ligation and resection of the aneurysm is safe and curative.
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Clin Neurol Neurosurg · Nov 2014
Cerebral metabolism during experimental endotoxin shock and after preconditioning with monophosphoryl lipid A.
Preconditioning with low doses of monophosphoryl lipid A (MPL) has been shown to induce endotoxin tolerance and to reduce the metabolic and hemodynamic consequences of endotoxin shock. However, no data are available about the effects of endotoxin preconditioning on cerebral metabolism during endotoxemia. The study was designed to determine the effects of endotoxin preconditioning with MPL on cerebral metabolism via microdialysis compared to muscle tissue metabolism during experimental endotoxemia. ⋯ Preconditioning with low doses of MPL ameliorates the negative metabolic effects of endotoxin shock in muscle tissue. With regard to cerebral metabolism, the present study suggests that MLP preconditioning provides moderate advantages, at least in an experimental model of endotoxin shock.
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Clin Neurol Neurosurg · Oct 2014
Clinical features and surgical outcomes of sporadic cerebellar hemangioblastomas.
Sporadic hemangioblastomas show a strong preference for the cerebellum. We clarify the clinical characteristics and role of surgery in sporadic cerebellar hemangioblastomas. ⋯ Sporadic cerebellar hemangioblastomas are usually associated with cysts and are voluminous by the time of diagnosis. Because these tumors result in the mass effect of posterior fossa, surgical removal is preferable and safe, and can be a timely curative strategy to prevent neurological decline.
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Clin Neurol Neurosurg · Oct 2014
Review Meta AnalysisEffects of dexmedetomidine on outcomes following craniocerebral operation - a meta-analysis.
To evaluate the effect of dexmedetomidine on outcomes following craniocerebral operation and provide evidence for individualized medication. ⋯ Dexmedetomidine can reduce the hemodynamic response and play a role in brain protection.