The Journal of family practice
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Review Randomized Controlled Trial Comparative Study Clinical Trial
Colloids versus crystalloids in fluid resuscitation: an analysis of randomized controlled trials.
Controversy about fluid therapy in resuscitation has existed since the 1960s. The difficulty could be that fluid behavior at the lung capillary membrane level may vary depending on the patient's particular pathology. ⋯ Because there is no significant mortality-rate advantage to using colloids, and because the cost-effectiveness ratio for crystalloids is much lower than for colloids, it is concluded that crystalloids should always be used in resuscitation efforts.