The Journal of family practice
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Complex regional pain syndrome (CRPS) type 1 may be diagnosed by history and physical exam with no further testing. Several different diagnostic criteria have undergone validity testing: the 1993 IASP criteria, Bruehl's criteria, and Veldman's criteria; there is no compelling reason to recommend 1 set of criteria over the others. ⋯ Some cases of CRPS type 1 in post-stroke upper extremity hemiplegia (also known as shoulder-hand syndrome) may be prevented by early inpatient rehabilitation and avoidance of shoulder trauma to the affected arm. Some cases of post-fracture CRPS type 1 may be prevented with 500 mg vitamin C daily started upon diagnosis of fracture and continued through healing.
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Diverse classes of medications are associated with QT interval prolongation and expose patients to the risk of potentially fatal ventricular arrhythmias. Clinicians can minimize adverse events by avoiding prescription of multiple medications associated with QT interval prolongation in high-risk patients.