The Journal of the American Dental Association
-
Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Multicenter clinical trial of ibuprofen and acetaminophen in the treatment of postoperative dental pain.
Pharmacological management of pain for acute and chronic conditions has been guided by a scientific understanding of peripheral and central acting mechanisms for the control of inflammation as well as pain. Oral surgery pain is a reliable model to reference the effectiveness of commonly used analgesics such as ibuprofen and acetaminophen. ⋯ After 6 hours, the degree of pain relief and tolerance was assessed. Ibuprofen has important implications for postoperative pain in clinical practice.