The Journal of the American Dental Association
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Randomized Controlled Trial Comparative Study
A comparison of a refrigerant and a topical anesthetic gel as preinjection anesthetics: a clinical evaluation.
The authors used a split-mouth design to determine the effectiveness of a refrigerant compared with that of a topical anesthetic gel in reducing the pain experienced during a posterior palatal anesthetic injection. ⋯ The potential benefits of using a refrigerant rather than a topical anesthetic gel are pain reduction, decreased application time, ease of application and avoidance of displeasing taste.