Journal of the American Geriatrics Society
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Randomized Controlled Trial Multicenter Study
Prestroke factors associated with poststroke mortality and recovery in older women in the Women's Health Initiative.
To examine prestroke lifestyle factors associated with poststroke mortality and recovery in older women. ⋯ Potentially modifiable factors before stroke, including smoking, diabetes mellitus, and being underweight, were associated with greater poststroke mortality in older women. Being overweight or obese and physical activity before stroke were associated with lower poststroke mortality in older women.
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Randomized Controlled Trial Multicenter Study
Delirium outcomes in a randomized trial of blood transfusion thresholds in hospitalized older adults with hip fracture.
To determine whether a higher blood transfusion threshold would prevent new or worsening delirium symptoms in the hospital after hip fracture surgery. ⋯ Blood transfusion to maintain hemoglobin concentrations greater than 10 g/dL alone is unlikely to influence delirium severity or rate in individuals with hip fracture after surgery with a hemoglobin concentration less than 10 g/dL.
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Multicenter Study Comparative Study
Age, renal dysfunction, cardiovascular disease, and antihyperglycemic treatment in type 2 diabetes mellitus: findings from the Renal Insufficiency and Cardiovascular Events Italian Multicenter Study.
To assess the distribution of antihyperglycemic treatments according to age and renal function and its relationship with cardiovascular disease in type 2 diabetes mellitus (T2DM). ⋯ In real-life conditions, use of agents that are not recommended in elderly adults with diabetes mellitus with moderate to severe renal impairment is frequent, but metformin is associated with lower cardiovascular event rates even in these individuals.