Journal of the American Veterinary Medical Association
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J. Am. Vet. Med. Assoc. · Oct 1999
Randomized Controlled Trial Clinical TrialEffects of intramuscular administration of low doses of medetomidine and medetomidine-butorphanol in middle-aged and old dogs.
To determine effects of low doses of medetomidine administered with and without butorphanol and glycopyrrolate to middle-aged and old dogs. ⋯ Administration of medetomidine (10 micrograms/kg, i.m.) and butorphanol (0.2 mg/kg, i.m.) induced sedation and analgesia and reduced amounts of thiopental and isoflurane required for anesthesia in middle-aged and old dogs. Glycopyrrolate decreased frequency of medetomidine-associated adverse effects.