Journal of the American Veterinary Medical Association
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J. Am. Vet. Med. Assoc. · Apr 2006
Randomized Controlled TrialEvaluation of total intravenous anesthesia with propofol or ketamine-medetomidine-propofol combination in horses.
Objective-To compare the anesthetic and cardiorespiratory effects of total IV anesthesia with propofol (P-TIVA) or a ketamine-medetomidine-propofol combination (KMP-TIVA) in horses. Design-Randomized experimental trial. Animals-12 horses. ⋯ There was no significant difference in time to standing after cessation of anesthesia between groups. Recovery from KMP-TIVA and P-TIVA was considered good and satisfactory, respectively. Conclusions and Clinical Relevance-In horses, KMP-TIVA and P-TIVA provided clinically useful anesthesia; the ketamine-medetomidine infusion provided a sparing effect on propofol requirement for maintaining anesthesia.
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J. Am. Vet. Med. Assoc. · Apr 2006
Randomized Controlled TrialEffect of transdermally administered fentanyl on minimum alveolar concentration of isoflurane in normothermic and hypothermic dogs.
To determine whether the minimum alveolar concentration (MAC) of isoflurane was altered by transdermal administration of fentanyl in normothermic and hypothermic dogs. ⋯ Data suggest that transdermal administration of fentanyl significantly reduces isoflurane requirements in normothermic dogs. The isoflurane MAC-sparing effects of transdermal fentanyl are not apparent in hypothermic dogs.