Journal of the American Veterinary Medical Association
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J. Am. Vet. Med. Assoc. · Aug 2006
Randomized Controlled TrialEvaluation of the isoflurane-sparing effects of lidocaine and fentanyl during surgery in dogs.
To evaluate the isoflurane-sparing effects of lidocaine and fentanyl administered by constant rate infusion (CRI) during surgery in dogs. ⋯ Administration of fentanyl resulted in greater isoflurane sparing effect than did lidocaine. However, it appeared that the low heart rate induced by fentanyl may partially offset the improvement in mean arterial pressure that would be expected with reduced isoflurane requirements.