Journal of the American Veterinary Medical Association
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J. Am. Vet. Med. Assoc. · Feb 2013
Randomized Controlled TrialEffects of postanesthetic sedation with romifidine or xylazine on quality of recovery from isoflurane anesthesia in horses.
To test the hypothesis that postanesthetic sedation with romifidine would dose-dependently improve recovery quality of recovery from isoflurane anesthesia in horses more than postanesthetic sedation with xylazine. ⋯ In healthy adult horses anesthetized with isoflurane for > 1 hour, the results of this study supported the use of 20 μg of romifidine/kg, i.v., rather than lower romifidine doses or xylazine, for postanesthetic sedation to improve recovery quality.
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J. Am. Vet. Med. Assoc. · Feb 2013
Randomized Controlled TrialInfluence of ketamine on the cardiopulmonary effects of intramuscular administration of dexmedetomidine-buprenorphine with subsequent reversal with atipamezole in dogs.
To compare the cardiorespiratory effects of IM administration of dexmedetomidine-buprenorphine (DB) and dexmedetomidine-buprenorphine-ketamine (DBK) in dogs with subsequent reversal with atipamezole. ⋯ Adding ketamine to the DB combination allowed dogs to maintain a higher HR and delayed the onset of sinus arrhythmias but failed to provide a significantly higher CO because of a reduction in stroke volume.