Journal of the American Veterinary Medical Association
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J. Am. Vet. Med. Assoc. · May 2014
Randomized Controlled TrialPostoperative comparison of four perioperative analgesia protocols in dogs undergoing stifle joint surgery.
To compare 4 analgesic protocols in dogs undergoing stifle joint surgery. ⋯ Pain scores were similar among groups, and all 4 groups had similar rescue analgesia requirements and similar times to first administration of rescue analgesia. All 4 analgesic protocols provided acceptable analgesia for 24 hours after stifle joint surgery.
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J. Am. Vet. Med. Assoc. · May 2014
Type II error and statistical power in reports of small animal clinical trials.
To describe reporting of key methodological elements associated with type II error in published reports of small animal randomized controlled trials (RCTs) and to determine the statistical power in a subset of RCTs with negative results. ⋯ The present survey found that small animal RCTs with negative results were often underpowered to detect moderate-to-large effect sizes between study groups. Information needed for critical appraisal was missing from most reports. The potential for clinicians to base treatment decisions on inappropriate interpretations of RCTs was worrisome. Design and reporting of small animal RCTs must be improved.
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J. Am. Vet. Med. Assoc. · Apr 2014
Randomized Controlled TrialCardiovascular effects of orotracheal intubation following anesthetic induction with propofol, ketamine-propofol, or ketamine-diazepam in premedicated dogs.
To compare the hemodynamic responses to orotracheal intubation following induction of anesthesia with propofol, ketamine-propofol, and ketamine-diazepam in premedicated dogs. ⋯ Intubation after anesthetic induction with ketamine-diazepam caused transitory hypertension, whereas intubation after induction with propofol or ketamine-propofol did not cause cardiovascular stimulation. In dogs in which hypertension is a concern, propofol or ketamine-propofol may be a better choice for induction prior to orotracheal intubation.
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J. Am. Vet. Med. Assoc. · Apr 2014
Randomized Controlled TrialEffects of maropitant, acepromazine, and electroacupuncture on vomiting associated with administration of morphine in dogs.
To evaluate effects of maropitant, acepromazine, and electroacupuncture on morphine-related signs of nausea and vomiting in dogs and assess sedative effects of the treatments. ⋯ Maropitant treatment was associated with a lower incidence of vomiting and retching, compared with control treatments, and acepromazine and electroacupuncture appeared to prevent an increase in severity of nausea following morphine administration in dogs.