Journal of the National Cancer Institute
-
J. Natl. Cancer Inst. · Sep 2000
Randomized Controlled Trial Multicenter Study Clinical TrialCanadian National Breast Screening Study-2: 13-year results of a randomized trial in women aged 50-59 years.
Screening for breast cancer with mammography in women aged 50 years or more has been shown to reduce mortality from breast cancer. However, the extent to which mammography contributes to the reduction of mortality in women who also undergo physical examination of the breasts is not known. This study was designed to compare breast cancer mortality following annual screening consisting of two-view mammography and physical examination of the breasts with mortality following annual screening by physical examination only. Breast self-examination was taught to all participants. ⋯ In women aged 50-59 years, the addition of annual mammography screening to physical examination has no impact on breast cancer mortality.