Journal of the National Cancer Institute
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J. Natl. Cancer Inst. · Sep 2001
Randomized Controlled Trial Comparative Study Clinical TrialFluorescence versus white-light bronchoscopy for detection of preneoplastic lesions: a randomized study.
There are no currently approved methods for the screening and early detection of lung cancer. We compared the ability of conventional white-light bronchoscopy (WLB) and laser-induced fluorescence endoscopy (LIFE) to detect preneoplastic lung lesions in a randomized trial in which both the order of the procedures and the bronchoscopists were randomly assigned. ⋯ LIFE was more sensitive than WLB in detecting preneoplastic bronchial changes in high-risk subjects. The prognostic implication of this finding is not yet clear.
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J. Natl. Cancer Inst. · Sep 2001
Comment Letter Comparative StudyRe: Prognosis and treatment of patients with breast tumors of one centimeter or less and negative axillary lymph nodes.