Journal of the National Cancer Institute
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J. Natl. Cancer Inst. · Apr 2014
Randomized Controlled Trial Multicenter StudyMagnetic resonance-guided focused ultrasound for patients with painful bone metastases: phase III trial results.
Pain due to bone metastases is a common cause of cancer-related morbidity, with few options available for patients refractory to medical therapies and who do not respond to radiation therapy. This study assessed the safety and efficacy of magnetic resonance-guided focused ultrasound surgery (MRgFUS), a noninvasive method of thermal tissue ablation for palliation of pain due to bone metastases. ⋯ This multicenter phase III trial demonstrated that MRgFUS is a safe and effective, noninvasive treatment for alleviating pain resulting from bone metastases in patients that have failed standard treatments.