Journal of the National Cancer Institute
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J. Natl. Cancer Inst.
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J. Natl. Cancer Inst. · Aug 2014
Survival outcomes after contralateral prophylactic mastectomy: a decision analysis.
Contralateral prophylactic mastectomy (CPM) rates have substantially increased in recent years and may reflect an exaggerated perceived benefit from the procedure. The objective of this study was to evaluate the magnitude of the survival benefit of CPM for women with unilateral breast cancer. ⋯ The absolute 20-year survival benefit from CPM was less than 1% among all age, ER status, and cancer stage groups. Estimates of LE gains and survival differences derived from decision models may provide more realistic expectations of CPM.