Journal of the National Cancer Institute
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J. Natl. Cancer Inst. · Jun 2012
The Diesel Exhaust in Miners study: a nested case-control study of lung cancer and diesel exhaust.
Most studies of the association between diesel exhaust exposure and lung cancer suggest a modest, but consistent, increased risk. However, to our knowledge, no study to date has had quantitative data on historical diesel exposure coupled with adequate sample size to evaluate the exposure-response relationship between diesel exhaust and lung cancer. Our purpose was to evaluate the relationship between quantitative estimates of exposure to diesel exhaust and lung cancer mortality after adjustment for smoking and other potential confounders. ⋯ Our findings provide further evidence that diesel exhaust exposure may cause lung cancer in humans and may represent a potential public health burden.
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J. Natl. Cancer Inst. · Jun 2012
The Diesel Exhaust in Miners study: a cohort mortality study with emphasis on lung cancer.
Current information points to an association between diesel exhaust exposure and lung cancer and other mortality outcomes, but uncertainties remain. ⋯ The study findings provide further evidence that exposure to diesel exhaust increases risk of mortality from lung cancer and have important public health implications.