Journal of the National Cancer Institute
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J. Natl. Cancer Inst. · Dec 2008
Risk of second malignancies in survivors of retinoblastoma: more than 40 years of follow-up.
Survivors of hereditary retinoblastoma have an elevated risk of developing second malignancies, but data on the risk in middle-aged retinoblastoma survivors (ie, those with more than 40 years of follow-up) are scarce. ⋯ Our analysis of middle-aged hereditary retinoblastoma survivors suggests that these individuals have an excess risk of epithelial cancer. Lifelong follow-up studies are needed to evaluate the full spectrum of subsequent cancer risk in hereditary retinoblastoma survivors.
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J. Natl. Cancer Inst. · Dec 2008
Productivity costs of cancer mortality in the United States: 2000-2020.
A model that predicts the economic benefit of reduced cancer mortality provides critical information for allocating scarce resources to the interventions with the greatest benefits. ⋯ Investments in programs that target the cancers with high incidence and/or cancers that occur in younger, working-age individuals are likely to yield the greatest reductions in productivity losses to society.
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J. Natl. Cancer Inst. · Dec 2008
Estimates and projections of value of life lost from cancer deaths in the United States.
Value-of-life methods are increasingly used in policy analyses of the economic burden of disease. The purpose of this study was to estimate and project the value of life lost from cancer deaths in the United States. ⋯ Estimated value of life lost due to cancer deaths in the United States is substantial and expected to increase dramatically, even if mortality rates remain constant, because of expected population changes. These estimates and projections may help target investments in cancer control strategies to tumor sites that are likely to result in the greatest burden of disease and to interventions that are the most cost-effective.
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J. Natl. Cancer Inst. · Dec 2008
Meta AnalysisFat, protein, and meat consumption and renal cell cancer risk: a pooled analysis of 13 prospective studies.
Results of several case-control studies suggest that high consumption of meat (all meat, red meat, or processed meat) is associated with an increased risk of renal cell cancer, but only a few prospective studies have examined the associations of intakes of meat, fat, and protein with renal cell cancer. ⋯ Intakes of fat and protein or their subtypes, red meat, processed meat, poultry, and seafood are not associated with risk of renal cell cancer.