British journal of clinical pharmacology
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Br J Clin Pharmacol · Jul 2004
ReviewAlprazolam is relatively more toxic than other benzodiazepines in overdose.
To describe alprazolam poisoning and the relative toxicity of alprazolam compared with other benzodiazepines. ⋯ Alprazolam was significantly more toxic than other benzodiazepines. The increased prescription of alprazolam to groups with an increased risk of deliberate self poisoning is concerning and needs review.
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The Consolidated Standards for Reporting Trials (CONSORT) are recommendations for improving the quality of reports of randomized controlled trials (RCTs). ⋯ The use of the selected CONSORT items is limited in these journals, possibly as many items may not be relevant to the types of studies published in clinical pharmacology journals. Further efforts are required to determine the applicability of CONSORT to RCTs in clinical pharmacology.