British journal of clinical pharmacology
-
Br J Clin Pharmacol · Jul 2021
ReviewSubgroup analysis in haematologic malignancies phase III clinical trials: A systematic review.
To assess the appropriateness of the use and interpretation of subgroup analysis in haematology randomized clinical trials (RCTs). ⋯ The subgroup claims reported in haematology RCTs lack credibility, even when the claims are strong. Information about subgroup difference should be interpreted cautiously.