Medical hypotheses
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Permanent injury to the nervous system can occur in a number of ways and lead to profound residual disability. Attempts to restore function are being made by many different groups. They range from prosthetic repair to pharmacological intervention. ⋯ One is proposed. From it a rational set of approaches to the restoration of nervous system function is generated. These are outlined.
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Placebo-controlled studies of effects of monosodium L-glutamate (MSG) and mixed synthetic food dyes in humans which have led to claims that these additives are safe in general use may be questioned on 3 methodological grounds: both active substance and placebo may be inadequately specified in published reports and potent common food allergens are used as placebos.