Journal of neurosurgery
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Journal of neurosurgery · Feb 2003
Randomized Controlled Trial Multicenter Study Clinical TrialLack of benefit of endoscopic ventriculoperitoneal shunt insertion: a multicenter randomized trial.
Endoscopically assisted ventricular catheter placement has been reported to reduce shunt failure in uncontrolled series. The authors investigated the efficacy of this procedure in a prospective multicenter randomized trial. ⋯ Endoscopic insertion of the initial VP shunt in children suffering from hydrocephalus did not reduce the incidence of shunt failure.
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Journal of neurosurgery · Feb 2003
Multicenter Study Clinical TrialLong-term intrathecal baclofen therapy for severe spasticity of cerebral origin.
The goal of this study was to ascertain the long-term effectiveness and safety of intrathecal baclofen (ITB) in the treatment of spasticity of cerebral origin in children and young adults. ⋯ Intrathecal baclofen provides effective long-term treatment of spasticity of cerebral origin and its effects do not appear to diminish with time. This therapy is frequently associated with adverse side effects that usually can be alleviated by adjustments in dosage.