Journal of neurosurgery
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Journal of neurosurgery · Jan 2025
Prognostic factors for long-term outcomes of bilateral pallidal deep brain stimulation in the treatment of Meige syndrome.
This study aimed to investigate the effects of bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) on both motor and nonmotor symptoms in patients with Meige syndrome and to further explore prognostic factors for postoperative outcomes based on the long-term follow-up results. ⋯ Bilateral GPi-DBS is an effective, safe, and promising treatment option for intractable Meige syndrome and provides sustained benefits in motor function and quality of life without inducing cognitive or mood-related side effects. Early intervention and accurate electrode placement in the sensorimotor subregion of the GPi are essential for optimizing long-term therapeutic outcomes.
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Journal of neurosurgery · Jan 2025
Clinical and radiological presentation of cavernomas according to the Zabramski classification.
Cerebral cavernous malformations (CCMs) are a cluster of abnormal vessels of the brain. CCMs have a low risk for intracerebral hemorrhage and appear increasingly often as incidental findings on MRI. Zabramski classification has been used to describe the radiological features of CCMs. How the Zabramski classification associates with the clinical symptoms at presentation and clinical course of the disease is not well established. ⋯ Most CCMs are asymptomatic, incidental findings, in particular, nearly all Zabramski type IV CCMs. If symptoms are present, they are mainly associated with Zabramski type I CCMs and occasionally with Zabramski type II or III CCMs. Although most Zabramski type I CCMs will regress to type II or III and remain asymptomatic, over long-term follow-up, up to one-quarter develop new symptoms.
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Journal of neurosurgery · Jan 2025
The effect of delayed-release antibiotics on the rate of postoperative wound infection for implanted neuromodulatory devices.
Implanted neuromodulatory devices are important for the surgical management of pain, epilepsy, movement disorders, and spasticity. These devices are surgically implanted, but many must be periodically explanted and replaced as batteries deplete or devices fail. Replacement surgery risks further infections that require device explantation, incur large financial costs, and reduce patient quality of life. To reduce infection rates, a single surgeon began using vancomycin-impregnated absorbable calcium sulfate delayed-response beads with neuromodulatory device and intrathecal pump primary implantations and replacements. The infection rates when using vancomycin-impregnated beads were compared with previously published rates from the same surgeon. ⋯ The use of vancomycin-impregnated absorbable calcium sulfate beads was associated with a reduced rate of postoperative infection rates with implantable devices, and specifically for DBS primary implantation and replacement surgeries.
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Journal of neurosurgery · Jan 2025
Evaluation of diversity, equity, and inclusion information on US neurosurgery residency program websites.
The objective of this study was to determine the prevalence of diversity, equity, and inclusion (DEI) information on neurosurgery residency program websites and examine the association between program size, ranking, and DEI information presence. ⋯ Most US neurosurgery residency programs lack DEI information on their websites. Larger programs and those with higher rankings are more likely to include DEI content, particularly standalone statements. Programs meeting DEI criteria tend to have a higher representation of female and Black residents. These findings highlight the need for greater transparency and commitment to DEI in neurosurgery residency programs, ensuring prospective applicants have access to comprehensive DEI information.