Bulletin of the World Health Organization
-
Bull. World Health Organ. · Sep 2020
Melanie Saville: the end-to-end process needed for a SARS-CoV-2 vaccine.
Melanie Saville talks to Gary Humphreys about the specific challenges faced in developing and distributing SARS-CoV-2 vaccines and the need to fund end-to-end approaches to support those aims.
-
Bull. World Health Organ. · Sep 2020
Simulation of pooled-sample analysis strategies for COVID-19 mass testing.
To evaluate two pooled-sample analysis strategies (a routine high-throughput approach and a novel context-sensitive approach) for mass testing during the coronavirus disease 2019 (COVID-19) pandemic, with an emphasis on the number of tests required to screen a population. ⋯ Pooled-sample PCR screening could save resources during COVID-19 mass testing. In particular, the novel context-sensitive approach, which uses pooled samples from homogeneous population groups, could substantially reduce the number of tests required to screen a population. Pooled-sample approaches could help countries sustain population screening over extended periods of time and thereby help contain foreseeable second-wave outbreaks.