Revista da Sociedade Brasileira de Medicina Tropical
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Rev. Soc. Bras. Med. Trop. · Jan 2020
Case ReportsCOVID-19 and acute pulmonary embolism: what should be considered to indicate a computed tomography pulmonary angiography scan?
The full spectrum of COVID-19 is still emerging, although several studies have highlighted that patients infected with the novel coronavirus can potentially develop a hypercoagulable state. However, several aspects related to the incidence and pathophysiology of the association between COVID-19 and pulmonary embolism are not well established. Here, we present a case of a patient with COVID-19 who developed acute pulmonary embolism. Clinical and laboratory data and findings of non-enhanced CT indicate possibility of acute pulmonary embolism, and support the decision to proceed with computed tomography pulmonary angiography that can objectively identify filling defects in pulmonary arterial branches.
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Rev. Soc. Bras. Med. Trop. · Jan 2020
Current evidence of neurological features, diagnosis, and neuropathogenesis associated with COVID-19.
Recent reports indicate that besides respiratory and systemic symptoms among coronavirus disease (COVID-19) patients, the disease has a wide spectrum of neurological manifestations (encephalitis, meningitis, myelitis, acute disseminated encephalomyelitis, metabolic and acute hemorrhagic necrotizing encephalopathy, cerebrovascular diseases, Guillain-Barré syndrome, polyneuritis cranialis, dysautonomia, and myopathies). The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can spread from the respiratory system to the central nervous system, using transneuronal and hematogenous mechanisms. ⋯ These aspects are relevant for correct diagnosis and treatment, and for the potential development of vaccines. This review highlights the latest evidence of SARS-CoV-2 infection with a focus on neurological involvement and potential neuropathogenesis mechanisms.
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Rev. Soc. Bras. Med. Trop. · Jan 2020
ReviewCare for frontline health care workers in times of COVID-19.
The spread of the 2019 coronavirus disease (COVID-19) has generated the collapse of health care systems and significant impacts on the health of the workers involved in combatting the disease worldwide. ⋯ A sensitive view of the health care worker's care is urgently needed to maintain the quality of health service offered to the population and preserve the health of frontline workers.
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Rev. Soc. Bras. Med. Trop. · Jan 2020
Case ReportsIschemic stroke related to HIV and SARS-COV-2 co-infection: a case report.
A 56-year-old male with human immunodeficiency virus required hospitalization due to the onset of both dyspnea and asthenia. A computed tomography of the chest exam showed the radiological pattern of coronavirus SARS-CoV-2 pulmonary involvement. ⋯ T1-weighted magnetic resonance sequence of the brain showed an area of hypointensity with a high intrinsic cortical signal and hyperintensity in the T2-sequence. A Doppler velocimetric examination showed total/critical sub occlusion, suggesting an ischemic stroke.
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Rev. Soc. Bras. Med. Trop. · Jan 2020
Is it time to talk about the end of social distancing? A joinpoint analysis of COVID-19 time series in Brazilian capitals.
Monitoring coronavirus disease (COVID-19)-related infections and deaths in Brazil is controversial, with increasing pressure to ease social distance measures. However, no evidence of a sustained, widespread fall in cases exists. ⋯ Caution is warranted when considering the relaxation of restrictions.