Revista do Instituto de Medicina Tropical de São Paulo
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Rev. Inst. Med. Trop. Sao Paulo · Apr 2017
Comparative StudyPrevalence and titers of yellow fever virus neutralizing antibodies in previously vaccinated adults.
The World Health Organization (WHO) recommends one single dose of the Yellow Fever (YF) vaccine based on studies of antibody persistency in healthy adults. We assessed the prevalence and titers of YF virus neutralizing antibodies in previously vaccinated persons aged 60 years, in comparison to younger adults. We also evaluated the correlation between antibody titers and the time since vaccination among participants who received one vaccine dose, and the seropositivity among participants vaccinated prior to or within the past 10 years. ⋯ the clinical relevance of the observed difference in YF virus neutralizing antibody titers between the two groups is not clear.