RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
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Using a 1.5 Tesla whole body system, image-guided localized 31P NMR spectra of normal brain tissue and of various intracranial tumours have been obtained. The spectra of normal brain tissue were reproducible, although further studies are necessary to determine physiological variability. ⋯ In follow-up studies of brain tumours undergoing treatment by chemotherapy or radiotherapy 31P MR spectroscopy demonstrated metabolic changes at a time when 1H MR imaging did not show any changes in tumour size or structure. Further investigations have to be done in order to evaluate the usefulness of 31P MRS for detecting therapeutic response in follow-up studies.