RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
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Comparative Study
[Early prediction of treatment response to high-dose chemotherapy in patients with relapsed germ cell tumors using [18F]FDG-PET, CT or MRI, and tumor marker].
To assess the ability of [(18)F]FDG-PET, CT/MRI and serum tumor marker (TM) for the early prediction of response in patients with metastatic germ cell tumors (GCT) undergoing salvage high-dose chemotherapy (HD-CTX). ⋯ FDG-PET has a high prognostic value for predicting the response to chemotherapy in patients with metastatic GCT early in the course of treatment and may improve patient selection for subsequent HD-CTX protocols. Especially in patients with response to induction chemotherapy according to CT or TM evaluation, PET offers additional information to detect patients with an overall unfavorable outcome.
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Comparative Study
Sensitivity encoding (SENSE) for high spatial resolution time-of-flight MR angiography of the intracranial arteries at 3.0 T.
1) To evaluate feasibility of sensitivity encoding (SENSE) for high spatial resolution intracranial 3D time-of-flight (TOF) MR angiography at 3.0 T using a 1024 imaging matrix and 2) to compare image quality and diagnostic yield with 3.0 T TOF MRA without SENSE. ⋯ The use of SENSE for intracranial TOF MRA at very high imaging matrix is feasible at 3.0 T. Compared to the imaging technique without SENSE, it allows TOF MRA with substantially reduced acquisition time, and with substantially increased anatomic coverage while maintaining image quality of NS-MRA.