RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
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Randomized Controlled Trial
Quantification of pulmonary perfusion with free-breathing dynamic contrast-enhanced MRI--a pilot study in healthy volunteers.
The assessment of pulmonary perfusion using dynamic contrast-enhanced (DCE) MRI is still limited in the clinical routine due to the necessity of breath holding. An acquisition technique for the quantitative assessment of pulmonary perfusion in free breathing was investigated in our study. ⋯ Free-breathing DCE-MRI appears to be suitable for the quantitative assessment of the pulmonary perfusion in healthy volunteers. The proposed segmentation and quantification approach does not suffer from the increased motion, as compared to the breath-holding measurement. The increased PPV and PPF during free breathing are in accordance with the results of previous studies concerning breathing influence on perfusion parameters. Overall, free-breathing DCE-MRI may be a promising technique for the assessment of pulmonary perfusion in various pathologies.