Pain
-
The Italian version of the McGill Pain Questionnaire (MPQ) is presented. Unlike Melzack's version, it was developed by employing 3 groups of normal subjects, excluding physicians or patients suffering from chronic pain. ⋯ Procedure was also basically the same. The Italian version of the MPQ joins the English, French and Finnish ones and might provide the basis for future cross-cultural studies.
-
Comparative Study Clinical Trial Controlled Clinical Trial
Efficacy and quality of ibuprofen and acetaminophen plus codeine analgesia.
Ibuprofen, 400 mg, was compared with 300 mg acetaminophen plus 30 mg of codeine and placebo in 120 post-orthopedic surgery patients with moderate to severe pain. The study was designed as a double-blind, single-dose, parallel-group analgesic efficacy assay. Estimates of analgesia were obtained up to 6 h using categorical and visual analog measures of pain intensity and pain relief. ⋯ Ibuprofen provided greater improvement in selected elements of mood than acetaminophen plus codeine at comparable levels of pain relief. While decreases in the sensory component of pain were most highly associated with pain relief provided by ibuprofen, decreases in the affective component were most highly associated with pain relief following acetaminophen plus codeine. These latter results indicate that mood assessment and the discrimination between sensory and affective components of pain could be particularly useful within analgesic drug assays, especially when comparing analgesics of differing pharmacologic class and when comparing the results of such assays in pain syndromes characterized by differing pain quality.