Journal of endodontics
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Journal of endodontics · Sep 2012
Comparative StudyComparison of the efficacy of a custom-made pulse oximeter probe with digital electric pulp tester, cold spray, and rubber cup for assessing pulp vitality.
The ideal technique for the evaluation of pulp vitality should be noninvasive, painless, objective, reliable, and reproducible. To achieve this, the most routine tests are sensitivity tests. However, a major shortcoming with these tests is that they indirectly indicate pulp vitality by measuring a neural response. Pulse oximetry is a well-established oxygen saturation monitoring technique broadly used in medicine. However, its efficacy as the pulp vitality test should be evaluated. The aim of this study was to design and build a custom-made pulse oximeter dental probe and to evaluate its efficacy in comparison with electric pulp tester, cold spray, and a rubber cup in pulp vitality testing. ⋯ Pulp testing by using pulse oximetry is more reliable than the electric test, rubber cup, and cold spray. The custom-made pulse oximeter dental probe is an effective and objective method for pulp vitality assessment.
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Journal of endodontics · Sep 2012
Randomized Controlled Trial Comparative StudySuccess rate of single- versus two-visit root canal treatment of teeth with apical periodontitis: a randomized controlled trial.
The aim of this study was to evaluate the outcome of single- versus 2-visit root canal treatment of teeth with apical periodontitis after a 2-year follow-up period. ⋯ Several factors play an important role in the decision-making process of 1- versus 2-visit endodontics. Among these are objective factors like preoperative diagnosis, the ability to obtain infection control, root canal anatomy, procedural complications, and subjective factors like patients' signs and symptoms. This study provided evidence that with a treatment protocol with instrumentation to predefined larger apical instrumentation sizes and irrigation with a negative apical pressure system can lead to healing in cases of apical periodontitis, which is a significant finding compared with more dated studies that showed average healing of apical periodontitis cases. With the given sample size, there was no statistically significant difference between the 2 treatment modalities.
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Journal of endodontics · Aug 2012
Randomized Controlled Trial Comparative StudyEffect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Pain control after root canal treatment is of great importance in endodontic practice. The aim of the present study was to investigate the effect of a long-acting anesthetic (bupivacaine) on postoperative pain and the use of analgesics after root canal treatment. ⋯ Patients who received bupivacaine as the anesthetic agent for single-visit endodontic treatment of irreversible pulpitis in mandibular molars had significantly less early postoperative pain and used fewer analgesics than those who had lidocaine as the anesthetic.
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Journal of endodontics · Jun 2012
Randomized Controlled Trial Comparative StudyComparative evaluation of 1.8 mL and 3.6 mL of 2% lidocaine with 1:200,000 epinephrine for inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, randomized single-blind study.
There is a decrease in the anesthetic efficacy of inferior alveolar nerve blocks in patients with irreversible pulpitis. It was hypothesized that the increasing the volume of anesthetic solution may improve the success rates of dental pulp anesthesia in patients with pulpal pain. ⋯ Increasing the volume of 2% lidocaine to 3.6 mL improved the success rate as compared with 1.8 mL but did not give a clinical success rates of 100%.
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Journal of endodontics · Jun 2012
Cytidine-phosphate-guanosine oligonucleotides induce interleukin-8 production through activation of TLR9, MyD88, NF-κB, and ERK pathways in odontoblast cells.
Odontoblasts are involved in innate immunity against invading microorganisms. However, the mechanisms of host inflammatory responses to bacterial DNA in odontoblasts are not fully understood. The purpose of this study was to investigate whether microbial cytidine-phosphate-guanosine (CpG) DNA influences interleukin-8 (IL-8) expression in odontoblasts and the signaling pathways involved. ⋯ These data demonstrate that CpG ODN-induced IL-8 expression was mediated through TLR9, MyD88, NF-κB, and ERK pathways in MDPC-23 cells and suggest a possible role for the CpG DNA-mediated immune response in odontoblasts with involvement of TLR9, MyD88, and ERK pathways in this process.