European urology
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Randomized Controlled Trial Multicenter Study Comparative Study
A placebo-controlled comparison of the efficiency of triple- and monotherapy in category III B chronic pelvic pain syndrome (CPPS).
To perform a prospective, placebo-controlled study to examine the efficacy of alpha-blocker compared with triple therapy (alpha-blocker, anti-inflammatory, and muscle relaxant) in the treatment of Category IIIB chronic pelvic pain syndrome (Category IIIB CPPS). ⋯ We found that alpha-blocker monotherapy was as effective and safe as triple therapy in the treatment of Category IIIB CPPS.
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A 62-yr-old woman with a 2-cm enhancing renal mass in the right moiety of a horseshoe kidney was treated via a four-port transperitoneal laparoscopic approach. The tumour was excised by cold scissors, and the parenchyma was sutured with Vicryl 1 sutures with Surgicel bolster and by using pledgets of Hem-o-lok((R)) clips. To our knowledge, this is the first report of a partial nephrectomy for tumour excision on a horseshoe kidney by a transperitoneal laparoscopic approach.
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An animal model for nonbacterial prostatitis in rats was developed with the use of intraprostatic injection of capsaicin, an agent thought to excite C-afferent fibers and cause neurogenic inflammation. The analgesic and anti-inflammatory properties of botulinum toxin type A (BoNT-A) was tested in this model. ⋯ Intraprostatic capsaicin injection induced neurogenic prostatitis and prostatic pain, and may be a useful research model. BoNT-A produced anti-inflammatory and analgesic effects, and support clinical evaluation in prostatitis.