Drug and alcohol dependence
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Drug Alcohol Depend · Jun 2020
Characterizing the polytobacco behaviors of sexual minority young adult college students.
Polytobacco use is a growing concern; users are exposed to cumulatively more nicotine, increasing their risk for dependence and long-term use. More sexual minority (SM) young adults report polytobacco use than their heterosexual peers, yet no studies explore how their tobacco patterns vary across the diverse product landscape. The purpose of this study was to characterize SM young adults' patterns of tobacco use and nicotine dependence, and explore co-occurring risk factors for polytobacco use. ⋯ SM young adults' tobacco use varies across the diverse product landscape. Failing to account for a range of tobacco behaviors and nicotine dependence prevents tailoring interventions that should also address concerns such as depressive symptoms, cannabis use, and binge alcohol use.
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Drug Alcohol Depend · Jun 2020
Variation in the degree of concentration of prescription opioid utilization using different measures.
Studies of opioid prescribing patterns have shown that a small percentage of prescribers are responsible for a large portion of total prescriptions. There is some evidence that prescription opioid use may be similarly concentrated, but patterns may differ by population and choice of opioid utilization measure. The objective of this study is to determine what proportion of prescription opioid utilization was attributable to the top utilizers among Medicaid beneficiaries and how this proportion varies by the measure used. ⋯ A small percentage of prescription opioid users account for a large share of prescription opioid use. Policy efforts should use metrics pertaining to days supply and total MME, not numbers of prescriptions, to more efficiently target heavy utilization. Policies targeting high-dose prescribing should consider the different ways that overlapping prescriptions may be taken.
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In response to the role overprescribing has played in the U.S. opioid crisis, in the past decade states have enacted four main types of laws to curb opioid prescribing: mandatory prescription drug monitoring program (PDMP) enrollment laws requiring clinicians to register with a PDMP; mandatory PDMP query laws requiring clinicians to check a PDMP prior to prescribing opioids; pill mill laws regulating pain management clinics; and opioid prescribing cap laws limiting the dose/duration of opioid prescriptions. While 47 states now have one or more of these laws in place, little is known about implementation and enforcement strategies, facilitators, and barriers. ⋯ Despite differing approaches, our findings suggest similar barriers to implementation and enforcement across state opioid prescribing laws. Strategies are needed to ease implementation and enforcement of laws that apply only to specific sub-sets of providers, patients, or prescriptions and address issues of access and data utilization of the PDMP.
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Drug Alcohol Depend · Jun 2020
Change in opioid policies in New England emergency departments, 2014 vs 2018.
The U.S. opioid epidemic persists, yet it is unclear if opioid-related emergency department (ED) policies have changed. We investigated: 1) the prevalence of opioid use disorder (OUD) prevention and treatment policies in New England EDs in 2018, and 2) how these policies have changed since 2014. ⋯ Implementation of opioid-related ED policies increased between 2014 and 2018. Continued effort is needed to understand the extent to which policy implementation translates to clinical care, and to best translate evidence-based policies into clinical practice.
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Drug Alcohol Depend · Jun 2020
Clinical TrialOpioid withdrawal symptoms, frequency, and pain characteristics as correlates of health risk among people who inject drugs.
Opioid withdrawal symptoms are widely understood to contribute to health risk but have rarely been measured in community samples of opioid using people who inject drugs (PWID). ⋯ Withdrawal symptoms among PWID increase health risk. Treatment of withdrawal symptoms is urgently needed and should include buprenorphine dispensing.