Drug and alcohol dependence
-
Drug Alcohol Depend · Dec 1987
ReviewPharmacological characteristics of agonist-antagonist analgesics.
A brief history and pharmacological characteristics of agonist-antagonist analgesics are presented. The importance of this class of compounds on the development of opioid-receptor concepts is described.
-
Drug Alcohol Depend · Nov 1987
Decreased serum selenium and magnesium levels in drunkenness arrestees.
Serum levels of selenium magnesium, copper, zinc and iron were studied in chronic drunkenness arrestees and a healthy control group. The mean serum concentrations of selenium and magnesium were both significantly lower (P less than 0.01) in drunkenness arrestees than in the control subjects. The mean alcohol intake was 190 g of absolute alcohol daily in drunkenness arrestees and 14 g in controls. The erythrocyte glutathione peroxidase concentrations of the study groups did not support poor selenium intake as a principal cause of low selenium concentration in the serum.
-
Drug Alcohol Depend · Sep 1987
ReviewCommunity-based approaches to highway safety: health promotion and drinking-driving.
Traditional preventive tactics in road safety have emphasized technology, legislation and regulation. There is growing awareness and evidence that these methods need to be complemented with alternative approaches, particularly those that acknowledge the importance of life style as a determinant of risky driving. Accordingly, new approaches are emerging that emphasize the need for long-term, individual and community-based approaches in road safety, particularly as a tactic for addressing complex problems, like drinking-driving, that are determined by psychosocial and life style factors.
-
'T's and B's' started to become widely used in Chicago in the early 1970s. Users reported an interaction between the two drugs which was expressed in slang terms such as 'Toms and Bettys', 'T'shirts and Blue Jeans.' By the late 1970s, T's and B's users occupied 10% of the treatment census in Chicago. Soft tissue damage was more pronounced with 'T's and B's' than with heroin and a number of serious medical complications were observed, e.g. pulmonary hypertension. The introduction of Talwin NX appears to have decreased greatly the use of T's and B's as demand for treatment for primary abuse of this combination is close to zero in 1983-84.