The Journal of antimicrobial chemotherapy
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J. Antimicrob. Chemother. · Feb 2009
Comparative StudyThe higher the number of daily doses of antibiotic treatment in lower respiratory tract infection the worse the compliance.
To assess the drug compliance observed among patients with lower respiratory tract infection treated with once-daily, twice-daily and thrice-daily antibiotic regimens. ⋯ The rate of compliance was very low, mainly when antibiotics were administered thrice daily and in regimens of 7 days or more. New strategies addressed to improve antibiotic drug compliance are, therefore, necessary.