The Journal of antimicrobial chemotherapy
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J. Antimicrob. Chemother. · Aug 2009
ReviewReporting of adverse events in randomized controlled trials of highly active antiretroviral therapy: systematic review.
Our objectives were to systematically assess the quality of reporting of adverse events (AEs) in publications of randomized trials of highly active antiretroviral therapy (HAART), and to examine whether reporting quality affects the effect estimates reported for AEs. ⋯ We found substantial variability in AE reporting. Variability was influenced by sponsor identity and affected outcomes. These facts obstruct our ability to choose HAART based on currently published data.