The Journal of antimicrobial chemotherapy
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J. Antimicrob. Chemother. · Mar 2012
Review Meta AnalysisAntibiotic prophylaxis in cardiac surgery: systematic review and meta-analysis.
Antibiotic prophylaxis is recommended in cardiac surgery. Current debate concerns the type of antibiotic(s), dosing and the duration of prophylaxis. ⋯ Evidence supports second- or third-generation cephalosporins for cardiac surgery prophylaxis and points at a possible advantage of prophylaxis prolongation up to 48 h post-operatively.